Gating window dependency on scanned carbon-ion beam dose distribution and imaging dose for thoracoabdominal treatment

Gating for scanned ion beam therapy

In treatment of motion affected tumours by means of a scanned particle beam severe under and over dosage can occur due to the interplay effect. By using gated beam delivery effective target motion is reduced, but even for the residual motion the interplay effect can lead to unsatisfactory dose distributions. Furthermore, an appropriate motion monitoring system is essential since beam delivery h...

Carbon-ion pencil beam scanning for thoracic treatment – initiation report and dose metrics evaluation

Carbon-ion beam scanning has not previously been used for moving tumor treatments. We have commenced respiratory-gated carbon-ion radiotherapy (CIRT) in the thoracic and abdominal regions under free-breathing conditions as a clinical trial. This study aimed to investigate this treatment in the lungs in comparison with passive scattering CIRT. Five patients had thoracic tumors treated with carbo...

Robustness of target dose coverage to motion uncertainties for scanned carbon ion beam tracking therapy of moving tumors.

Beam tracking with scanned carbon ion radiotherapy achieves highly conformal target dose by steering carbon pencil beams to follow moving tumors using real-time magnetic deflection and range modulation. The purpose of this study was to evaluate the robustness of target dose coverage from beam tracking in light of positional uncertainties of moving targets and beams. To accomplish this, we simul...

Development and validation of a scanned proton beam model for dose distribution verification using Monte Carlo

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Real-time dose compensation methods for scanned ion beam therapy of moving tumors